For example, the chance of death from overdosing on opiates is greatly increased when they are consumed in conjunction with alcohol. Poly drug use often carries more risk than use of a single drug, due to an increase in side effects, and drug synergy. Death can occur from overdosing on a single or multiple drugs, or from combined drug intoxication (CDI) due to poly drug use. Notable deaths from acute drug use include Mac Miller, Heath Ledger, Prince, Philip Seymour Hoffman, Dolores O'Riordan, and Michael Jackson.ĭrug overdose and intoxication are significant causes of accidental death and can also be used as a form of suicide. You can help by adding missing items with reliable sources. This is a dynamic list and may never be able to satisfy particular standards for completeness.
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